Problems with disabled accounts from former employees in your SharePoint User Profile Store ?

This will help you set up Exclusion Filters in the User Profile Synchronization

 

1) Browse to Central Administration Site > Manage Service Applications > User Profile Service Application.

2) On the Manage Profile Service: User Profile Service Application page, click the  Configure Synchronization Connections. This will take you to a page where all the synchronization connections are.

follow this excellent post from Spencer Harbar at harbar.net (http://www.harbar.net/archive/2011/02/22/323.aspx)

He explains how to set up filters with the userAccountControl attribute from AD user object.

  

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